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Thereafter, batches of 3 islets per condition were transferred into a 96-well plate containing 200 L KRB per well followed by the addition of 2.8 and 16.7 mM glucose (final concentrations) and the plate was incubated at 37 C for 1 h

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In post-hoc analyses at 24 weeks, the last time point before placebo participants were eligible for orforglipron as rescue therapy, the change in body weight from ATTAIN-MAINTAIN baseline for patients switching to orforglipron from Wegovy was -0.1 kg vs